Silveira, Pablo A., Jordan, Margaret A., and Baxter, Alan G. (1999) Dissecting genetic mechanisms conferring susceptibility to autoimmune diseases. Current Allergy and Clinical Immunology, 12. pp. 10-16.

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Abstract

[Extract] Autoimmunity is defined as a specific immune response directed against one or more self antigens that occurs as a result of the failure or breakdown in the mechanisms responsible for maintaining immunological tolerance. Although autoimmunity is not necessarily destructive, in a small proportion of individuals, it can lead to pathological tissue damage. Depending on the target tissue of the autoimmune attack, a variety of autoimmune diseases can ensue which differ greatly in their clinical presentation.

Item ID:	21886
Item Type:	Article (Research - C1)
ISSN:	1609-3607
Related URLs:	Publisher
Date Deposited:	07 Jun 2012 00:57
FoR Codes:	11 MEDICAL AND HEALTH SCIENCES > 1107 Immunology > 110703 Autoimmunity @ 100%
SEO Codes:	92 HEALTH > 9299 Other Health > 929999 Health not elsewhere classified @ 100%
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